| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MTHFS |
| Gene ID: | 10588 |
| Uniprot ID: | MTHFS_HUMAN |
| Immunogen Region: | 1-203 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-203 of human MTHFS (NP_006432.1). |
| Immunogen Sequence: | MAAAAVSSAKRSLRGELKQR LRAMSAEERLRQSRVLSQKV IAHSEYQKSKRISIFLSMQD EIETEEIIKDIFQRGKICFI PRYRFQSNHMDMVRIESPEE ISLLPKTSWNIPQPGEGDVR EEALSTGGLDLIFMPGLGFD KHGNRLGRGKGYYDAYLKRC LQHQEVKPYTLALAFKEQIC LQVPVNENDMKVDEVLYEDS STA |
| Function | Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate. |
| Protein Name | 5-Formyltetrahydrofolate Cyclo-Ligase5 -10-Methenyl-Tetrahydrofolate SynthetaseMthfsMethenyl-Thf Synthetase |
| Database Links | Reactome: R-HSA-196757 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-5-Formyltetrahydrofolate Cyclo-Ligase antibodyAnti-5 -10-Methenyl-Tetrahydrofolate Synthetase antibodyAnti-Mthfs antibodyAnti-Methenyl-Thf Synthetase antibodyAnti-MTHFS antibody |
Information sourced from Uniprot.org