| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MTCH1 |
| Gene ID: | 23787 |
| Uniprot ID: | MTCH1_HUMAN |
| Immunogen Region: | 100-250 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 100-250 of human MTCH1 (NP_001258570.1). |
| Immunogen Sequence: | LYVKLLIQVGHEPMPPTLGT NVLGRKVLYLPSFFTYAKYI VQVDGKIGLFRGLSPRLMSN ALSTVTRGSMKKVFPPDEIE QVSNKDDMKTSLKKVVKETS YEMMMQCVSRMLAHPLHVIS MRCMVQFVGREAKYSGVLSS IGKIFKEEGLL |
| Tissue Specificity | Widely expressed with a predominant expression in brain. |
| Function | Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane. Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins. Does not mediate insertion of beta-barrel transmembrane proteins. May play a role in apoptosis. |
| Protein Name | Mitochondrial Carrier Homolog 1Presenilin-Associated Protein |
| Cellular Localisation | Mitochondrion Outer MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Carrier Homolog 1 antibodyAnti-Presenilin-Associated Protein antibodyAnti-MTCH1 antibodyAnti-PSAP antibodyAnti-CGI-64 antibodyAnti-UNQ1871 antibodyAnti-PRO4314 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and CD71/Transferrin Receptor knockout (KO) HeLa cells, using [KO Validated] CD71/Transferrin Receptor Rabbit polyclonal antibody (STJ11100056) at 1:5000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89127/357577/STJ11100056_1__62720.1713121708.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CD71/Transferrin Receptor knockout (KO) HeLa cells, using [KO Validated] CD71/Transferrin Receptor Rabbit polyclonal antibody (STJ11100056) at 1:5000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
