| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MSH5 |
| Gene ID: | 4439 |
| Uniprot ID: | MSH5_HUMAN |
| Immunogen Region: | 1-260 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human MSH5 (NP_751897.1). |
| Immunogen Sequence: | MASLGANPRRTPQGPRPGAA SSGFPSPAPVPGPREAEEEE VEEEEELAEIHLCVLWNSGY LGIAYYDTSDSTIHFMPDAP DHESLKLLQRVLDEINPQSV VTSAKQDENMTRFLGKLASQ EHREPKRPEIIFLPSVDFGL EISKQRLLSGNYSFIPDAMT ATEKILFLSSIIPFDCLLTV RALGGLLKFLGRRRIGVELE DYNVSVPILGFKKFMLTHLV NIDQDTYSVLQIFKSESHP |
| Tissue Specificity | Widely expressed, with high levels in testis and ovary, including granulosa cells. Also expressed in fetal ovary and adrenal gland. |
| Function | Involved in DNA mismatch repair and meiotic recombination processes. Facilitates crossovers between homologs during meiosis. |
| Protein Name | Muts Protein Homolog 5Hmsh5 |
| Database Links | Reactome: R-HSA-912446 |
| Alternative Antibody Names | Anti-Muts Protein Homolog 5 antibodyAnti-Hmsh5 antibodyAnti-MSH5 antibody |
Information sourced from Uniprot.org