Anti-MRC1 antibody (610-1456) (STJ111269)

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STJ111269
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:1000-1:5000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MRC1
Gene ID: 4360
Uniprot ID: MRC1_HUMAN
Immunogen Region: 610-1456
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 610-860 of human Mannose Receptor/CD206 (NP_002429.1).
Immunogen Sequence: GLWDVLKCDEKAKFVCKHWA EGVTHPPKPTTTPEPKCPED WGASSRTSLCFKLYAKGKHE KKTWFESRDFCRALGGDLAS INNKEEQQTIWRLITASGSY HKLFWLGLTYGSPSEGFTWS DGSPVSYENWAYGEPNNYQN VEYCGELKGDPTMSWNDINC EHLNNWICQIQKGQTPKPEP TPAPQDNPPVTEDGWVIYKD YQYYFSKEKETMDNARAFCK RNFGDLVSIQSESEKKFLW
Function Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as a phagocytic receptor for bacteria, fungi and other pathogens. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E. (Microbial infection) Interacts with Hepatitis B virus envelope protein.
Protein Name Macrophage Mannose Receptor 1
Mmr
C-Type Lectin Domain Family 13 Member D
C-Type Lectin Domain Family 13 Member D-Like
Human Mannose Receptor
Hmr
Macrophage Mannose Receptor 1-Like Protein 1
Cd Antigen Cd206
Database Links Reactome: R-HSA-1236978
Reactome: R-HSA-9637628
Cellular Localisation Endosome Membrane
Single-Pass Type I Membrane Protein
Cell Membrane
Alternative Antibody Names Anti-Macrophage Mannose Receptor 1 antibody
Anti-Mmr antibody
Anti-C-Type Lectin Domain Family 13 Member D antibody
Anti-C-Type Lectin Domain Family 13 Member D-Like antibody
Anti-Human Mannose Receptor antibody
Anti-Hmr antibody
Anti-Macrophage Mannose Receptor 1-Like Protein 1 antibody
Anti-Cd Antigen Cd206 antibody
Anti-MRC1 antibody
Anti-CLEC13D antibody
Anti-CLEC13DL antibody
Anti-MRC1L1 antibody

Information sourced from Uniprot.org