| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-MPP7 (340-390 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | MPP7 |
| Gene ID: | 143098 |
| Uniprot ID: | MPP7_HUMAN |
| Immunogen Region: | 340-390 aa |
| Specificity: | Specific for MPP7. |
| Immunogen: | A synthetic peptide from aa region 340-390 of human MPP7 conjugated to an immunogenic carrier protein was used as the antigen. The peptide shares 87% identity with rat sequence. |
| Function | Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact. |
| Protein Name | Maguk P55 Subfamily Member 7 |
| Database Links | Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013406Reactome: R-HSA-9013408Reactome: R-HSA-9013409Reactome: R-HSA-9013423 |
| Cellular Localisation | MembranePeripheral Membrane ProteinLateral Cell MembraneCell JunctionTight JunctionAdherens JunctionCytoplasmCell CortexIn Epidermal CellsDetected Primarily At The Lateral Cell Membrane |
| Alternative Antibody Names | Anti-Maguk P55 Subfamily Member 7 antibodyAnti-MPP7 antibody |
Information sourced from Uniprot.org
