| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MOCOS |
| Gene ID: | 55034 |
| Uniprot ID: | MOCOS_HUMAN |
| Immunogen Region: | 649-888 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 649-888 of human MOCOS (NP_060417.2). |
| Immunogen Sequence: | VIKAKGMEPIEVPLEENSER TQIRQSRVCADRVSTYDCGE KISSWLSTFFGRPCHLIKQS SNSQRNAKKKHGKDQLPGTM ATLSLVNEAQYLLINTSSIL ELHRQLNTSDENGKEELFSL KDLSLRFRANIIINGKRAFE EEKWDEISIGSLRFQVLGPC HRCQMICIDQQTGQRNQHVF QKLSESRETKVNFGMYLMHA SLDLSSPCFLSVGSQVLPVL KENVEGHDLPASEKHQDVT |
| Function | Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain is able to reduce N-hydroxylated prodrugs, such as benzamidoxime. |
| Protein Name | Molybdenum Cofactor SulfuraseMcsMosMoco SulfuraseHmcsMolybdenum Cofactor Sulfurtransferase |
| Database Links | Reactome: R-HSA-947581 |
| Alternative Antibody Names | Anti-Molybdenum Cofactor Sulfurase antibodyAnti-Mcs antibodyAnti-Mos antibodyAnti-Moco Sulfurase antibodyAnti-Hmcs antibodyAnti-Molybdenum Cofactor Sulfurtransferase antibodyAnti-MOCOS antibody |
Information sourced from Uniprot.org