![Anti-MITF antibody [34CA5] (STJ16101768)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/152274/347122/STJ16101768_1__87995.1681999391.jpg?c=1 "Anti-MITF antibody [34CA5] (STJ16101768)")
![Anti-MITF antibody [34CA5] (STJ16101768)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/152274/347122/STJ16101768_1__87995.1681999391.jpg?c=1 "Anti-MITF antibody [34CA5] (STJ16101768)")
| Host: | Mouse |
| Applications: | IHC-P/IHC-F |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Microphthalmia Transcription Factor is suitable for use in Immunohistochemistry and Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 34CA5 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | Tissue culture supernatant with 15mM Sodium azide |
| Dilution Range: | IHC-P 1:10-1:20IHC-F |
| Storage Instruction: | Store at 2-8°C upon receipt. |
| Immunogen: | Prokaryotic recombinant protein corresponding to 111 amino acids of the N-terminal region of the MITF-M molecule |
| Background | Microphthalmia transcription factor (MITF) gene product, a nuclear transcription factor of the basic-helix-loop-helix type, is thought to play a role in the regulation of genes encoding the enzymes necessary for melanogenesis. These include tyrosinase, TRP-1 and TRP-2. MITF is critical for the embryonic development and postnatal viability of melanocytes. The melanocyte-specific isoform of microphthalmia transcription factor MITF-M, is reported to be expressed in normal and malignant melanocytes. The other isoforms, MITF-A, MITF-C and MITF-H, differ structurally at the N-terminus from MITF-M. |
Information sourced from Uniprot.org