| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Glutathione S-transferase 3, mitochondrial (8-57 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MGST3 |
| Gene ID: | 4259 |
| Uniprot ID: | MGST3_HUMAN |
| Immunogen Region: | 8-57 aa |
| Specificity: | MGST3 Polyclonal Antibody detects endogenous levels of MGST3 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human MGST3 at the amino acid range 8-57 |
| Function | Displays both glutathione S-transferase and glutathione peroxidase activities toward oxyeicosanoids, as part of cellular detoxification as well as synthesis of bioactive metabolites. Catalyzes conjugate addition of reduced glutathione to the alpha, beta-unsaturated C=C carbonyl group of eisosanoids such as leukotriene A4 and 15-deoxy-Delta12,14-prostaglandin J2 to form GSH adducts relevant to the inflammatory response. Catalyzes glutathione-dependent reduction of eicosanoid peroxides to yield the corresponding eicosanoid hydroxides. |
| Protein Name | Glutathione S-Transferase 3 - MitochondrialGst-3Glutathione Peroxidase Mgst3Ltc4 Synthase Mgst3 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-5423646 |
| Cellular Localisation | Mitochondrion Outer MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Glutathione S-Transferase 3 - Mitochondrial antibodyAnti-Gst-3 antibodyAnti-Glutathione Peroxidase Mgst3 antibodyAnti-Ltc4 Synthase Mgst3 antibodyAnti-MGST3 antibody |
Information sourced from Uniprot.org