| Tissue Specificity | Widely expressed. Strongly overexpressed in pancreatic cancer. |
| Post Translational Modifications | N-glycosylated. |
| Function | Glycosyltransferase that catalyzes the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains. Prefers complex-type N-glycans over hybrid-types. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis. |
| Protein Name | Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase BN-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase IvbGlcnac-T IvbGnt-IvbN-Acetylglucosaminyltransferase IvbUdp-N-Acetylglucosamine - Alpha-1 -3-D-Mannoside Beta-1 -4-N-Acetylglucosaminyltransferase Ivb |
| Database Links | Reactome: R-HSA-9694548Reactome: R-HSA-975577 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinA Processed Soluble Form Also Exists |
| Alternative Antibody Names | Anti-Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase B antibodyAnti-N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase Ivb antibodyAnti-Glcnac-T Ivb antibodyAnti-Gnt-Ivb antibodyAnti-N-Acetylglucosaminyltransferase Ivb antibodyAnti-Udp-N-Acetylglucosamine - Alpha-1 -3-D-Mannoside Beta-1 -4-N-Acetylglucosaminyltransferase Ivb antibodyAnti-MGAT4B antibodyAnti-UNQ906 antibodyAnti-PRO1927 antibody |
Information sourced from Uniprot.org
