| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MGAT4B (409-548) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MGAT4B |
| Gene ID: |
11282 |
| Uniprot ID: |
MGT4B_HUMAN |
| Immunogen Region: |
409-548 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 409-548 of human MGAT4B (NP_055090.1). |
| Immunogen Sequence: |
TYQHFTLEKAYLREDFFWAF TPAAGDFIRFRFFQPLRLER FFFRSGNIEHPEDKLFNTSV EVLPFDNPQSDKEALQEGRT ATLRYPRSPDGYLQIGSFYK GVAEGEVDPAFGPLEALRLS IQTDSPVWVILSEIFLKKAD |
| Tissue Specificity | Widely expressed. Strongly overexpressed in pancreatic cancer. |
| Post Translational Modifications | N-glycosylated. |
| Function | Glycosyltransferase that catalyzes the transfer of GlcNAc from UDP-GlcNAc to the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans through a beta1-4 linkage and participates in the production of tri- and tetra-antennary N-linked sugar chains. Prefers complex-type N-glycans over hybrid-types. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis. |
| Protein Name | Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase BN-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase IvbGlcnac-T IvbGnt-IvbN-Acetylglucosaminyltransferase IvbUdp-N-Acetylglucosamine - Alpha-1 -3-D-Mannoside Beta-1 -4-N-Acetylglucosaminyltransferase Ivb |
| Database Links | Reactome: R-HSA-9694548Reactome: R-HSA-975577 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinA Processed Soluble Form Also Exists |
| Alternative Antibody Names | Anti-Alpha-1 -3-Mannosyl-Glycoprotein 4-Beta-N-Acetylglucosaminyltransferase B antibodyAnti-N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase Ivb antibodyAnti-Glcnac-T Ivb antibodyAnti-Gnt-Ivb antibodyAnti-N-Acetylglucosaminyltransferase Ivb antibodyAnti-Udp-N-Acetylglucosamine - Alpha-1 -3-D-Mannoside Beta-1 -4-N-Acetylglucosaminyltransferase Ivb antibodyAnti-MGAT4B antibodyAnti-UNQ906 antibodyAnti-PRO1927 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
