Anti-MEX3B antibody (1-70) (STJ119170)

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STJ119170
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MEX3B
Gene ID: 84206
Uniprot ID: MEX3B_HUMAN
Immunogen Region: 1-70
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human MEX3B (NP_115622.2).
Immunogen Sequence: MPSSLFADLERNGSGGGGGG SSGGGETLDDQRALQLALDQ LSLLGLDSDEGASLYDSEPR KKSVNMTECV
Tissue Specificity Highest levels found in fetal brain and testis. Detected in the adult intestinal epithelium, specifically in goblet cell at protein level.
Post Translational Modifications Phosphorylation at Ser-462 creates a docking site for 14-3-3, which stabilizes the protein and modulates its ability to bind RNA.
Function RNA-binding protein. May be involved in post-transcriptional regulatory mechanisms.
Protein Name Rna-Binding Protein Mex3b
Ring Finger And Kh Domain-Containing Protein 3
Ring Finger Protein 195
Cellular Localisation Nucleus
Cytoplasm
P-Body
Cytoplasmic Granule
Predominantly Expressed In The Cytoplasm And Shuttles Between The Cytoplasm And The Nucleus Through The Crm1 Export Pathway
Localization To P-Bodies Is Dependent On 14-3-3
Alternative Antibody Names Anti-Rna-Binding Protein Mex3b antibody
Anti-Ring Finger And Kh Domain-Containing Protein 3 antibody
Anti-Ring Finger Protein 195 antibody
Anti-MEX3B antibody
Anti-KIAA2009 antibody
Anti-RKHD3 antibody
Anti-RNF195 antibody

Information sourced from Uniprot.org