| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | METAP1 |
| Gene ID: | 23173 |
| Uniprot ID: | MAP11_HUMAN |
| Immunogen Region: | 177-386 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 177-386 of human METAP1 (NP_055958.2). |
| Immunogen Sequence: | RNCYPSPLNYYNFPKSCCTS VNEVICHGIPDRRPLQEGDI VNVDITLYRNGYHGDLNETF FVGEVDDGARKLVQTTYECL MQAIDAVKPGVRYRELGNII QKHAQANGFSVVRSYCGHGI HKLFHTAPNVPHYAKNKAVG VMKSGHVFTIEPMICEGGWQ DETWPDGWTAVTRDGKRSAQ FEHTLLVTDTGCEILTRRLD SARPHFMSQF |
| Function | Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle. |
| Protein Name | Methionine Aminopeptidase 1 Map 1 Metap 1 Peptidase M 1 |
| Database Links | Reactome: R-HSA-2514859 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Methionine Aminopeptidase 1 antibody Anti-Map 1 antibody Anti-Metap 1 antibody Anti-Peptidase M 1 antibody Anti-METAP1 antibody Anti-KIAA0094 antibody |
Information sourced from Uniprot.org