Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Protein Name | Mediator Of Rna Polymerase Ii Transcription Subunit 21Mediator Complex Subunit 21Rna Polymerase Ii Holoenzyme Component Srb7Rnapii Complex Component Srb7Hsrb7 |
Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-381340Reactome: R-HSA-9833110 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Mediator Of Rna Polymerase Ii Transcription Subunit 21 antibodyAnti-Mediator Complex Subunit 21 antibodyAnti-Rna Polymerase Ii Holoenzyme Component Srb7 antibodyAnti-Rnapii Complex Component Srb7 antibodyAnti-Hsrb7 antibodyAnti-MED21 antibodyAnti-SRB7 antibodyAnti-SURB7 antibody |
Information sourced from Uniprot.org