Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Acyl-protein thioesterase 2 (30-110 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | LYPLA2 |
Gene ID: | 11313 |
Uniprot ID: | LYPA2_HUMAN |
Immunogen Region: | 30-110 aa |
Specificity: | LYPA2 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 30-110 |
Function | Acts as an acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GSDMD, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide. |
Protein Name | Acyl-Protein Thioesterase 2Apt-2Lysophospholipase IiLpl-IiLysopla IiPalmitoyl-Protein Hydrolase |
Database Links | Reactome: R-HSA-373760 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Acyl-Protein Thioesterase 2 antibodyAnti-Apt-2 antibodyAnti-Lysophospholipase Ii antibodyAnti-Lpl-Ii antibodyAnti-Lysopla Ii antibodyAnti-Palmitoyl-Protein Hydrolase antibodyAnti-LYPLA2 antibodyAnti-APT2 antibody |
Information sourced from Uniprot.org