| Tissue Specificity | Highly expressed in proliferative tissues such as adult thymus and testis, and expressed at lower levels in uterus, small intestine, colon, and peripheral blood mononuclear cells. Also expressed in neoplastic cell lines including those derived from myeloid and lymphoid leukemias. |
| Function | Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis. |
| Protein Name | Lymphoid-Specific HelicaseProliferation-Associated Snf2-Like ProteinSwi/Snf2-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 6 |
| Database Links | Reactome: R-HSA-9839394 |
| Cellular Localisation | NucleusClosely Associated With Pericentric Heterochromatin |
| Alternative Antibody Names | Anti-Lymphoid-Specific Helicase antibodyAnti-Proliferation-Associated Snf2-Like Protein antibodyAnti-Swi/Snf2-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 6 antibodyAnti-HELLS antibodyAnti-PASG antibodyAnti-SMARCA6 antibodyAnti-Nbla10143 antibody |
Information sourced from Uniprot.org
