Tissue Specificity | Isoform 1 is expressed in many tissues. Not found in heart, liver, spleen and testis. Relatively highly expressed in fetal brain. Isoform LMX1A-4AB is expressed in testis. |
Function | Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae. |
Protein Name | Lim Homeobox Transcription Factor 1-AlphaLim/Homeobox Protein 1.1Lmx-1.1Lim/Homeobox Protein Lmx1a |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Lim Homeobox Transcription Factor 1-Alpha antibodyAnti-Lim/Homeobox Protein 1.1 antibodyAnti-Lmx-1.1 antibodyAnti-Lim/Homeobox Protein Lmx1a antibodyAnti-LMX1A antibody |
Information sourced from Uniprot.org