| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LIMS2 |
| Gene ID: | 55679 |
| Uniprot ID: | LIMS2_HUMAN |
| Immunogen Region: | 1-341 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-341 of human LIMS2 (NP_001154875.1). |
| Immunogen Sequence: | MTGSNMSDALANAVCQRCQA RFSPAERIVNSNGELYHEHC FVCAQCFRPFPEGLFYEFEG RKYCEHDFQMLFAPCCGSCG EFIIGRVIKAMNNNWHPGCF RCELCDVELADLGFVKNAGR HLCRPCHNREKAKGLGKYIC QRCHLVIDEQPLMFRSDAYH PDHFNCTHCGKELTAEAREL KGELYCLPCHDKMGVPICGA CRRPIEGRVVNALGKQWHVE HFVCAKCEKPFLGHRHYEK |
| Function | Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Plays a role in modulating cell spreading and migration. |
| Protein Name | Lim And Senescent Cell Antigen-Like-Containing Domain Protein 2Lim-Like Protein 2Particularly Interesting New Cys-His Protein 2Pinch-2 |
| Database Links | Reactome: R-HSA-446353 |
| Cellular Localisation | NucleusCell JunctionFocal AdhesionCell MembranePeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Lim And Senescent Cell Antigen-Like-Containing Domain Protein 2 antibodyAnti-Lim-Like Protein 2 antibodyAnti-Particularly Interesting New Cys-His Protein 2 antibodyAnti-Pinch-2 antibodyAnti-LIMS2 antibodyAnti-PINCH2 antibody |
Information sourced from Uniprot.org