| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-LEFTY2 (57-366) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
LEFTY2 |
| Gene ID: |
7044 |
| Uniprot ID: |
LFTY2_HUMAN |
| Immunogen Region: |
57-366 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 57-366 of human LEFTY2 (NP_003231.2). |
| Immunogen Sequence: |
VRAQYVVLLRRSHGDRSRGK RFSQSFREVAGRFLASEAST HLLVFGMEQRLPPNSELVQA VLRLFQEPVPKAALHRHGRL SPRSAQARVTVEWLRVRDDG SNRTSLIDSRLVSVHESGWK AFDVTEAVNFWQQLSRPRQP LLLQVSVQREHLGPLASGAH KLVRFASQGAPAGLGEPQLE LHTLDLRDYGAQGDCDPEAP MTEGTRCCRQEMYIDLQGMK WAKNWVLEPPGFLAYECVG |
| Tissue Specificity | Mesenchymal cells of the endometrial stroma. |
| Post Translational Modifications | The processing of the protein may also occur at the second R-X-X-R site located at AA 132-135. Processing appears to be regulated in a cell-type specific manner. |
| Function | Required for left-right (L-R) asymmetry determination of organ systems in mammals. May play a role in endometrial bleeding. |
| Protein Name | Left-Right Determination Factor 2Endometrial Bleeding-Associated FactorLeft-Right Determination Factor AProtein Lefty-2Protein Lefty-ATransforming Growth Factor Beta-4Tgf-Beta-4 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-1181150Reactome: R-HSA-1433617 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Left-Right Determination Factor 2 antibodyAnti-Endometrial Bleeding-Associated Factor antibodyAnti-Left-Right Determination Factor A antibodyAnti-Protein Lefty-2 antibodyAnti-Protein Lefty-A antibodyAnti-Transforming Growth Factor Beta-4 antibodyAnti-Tgf-Beta-4 antibodyAnti-LEFTY2 antibodyAnti-EBAF antibodyAnti-LEFTA antibodyAnti-LEFTYA antibodyAnti-TGFB4 antibodyAnti-PSEC0024 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
