| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-KCNIP1 (N-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | KCNIP1 |
| Gene ID: | 30820 |
| Uniprot ID: | KCIP1_HUMAN |
| Immunogen Region: | N-Term |
| Specificity: | Specific for KCNIP1. |
| Immunogen: | A synthetic peptide from n-terminal region of rat KCNIP1, isoform 1 conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Increases the presence of KCND2 at the cell surface. |
| Protein Name | A-Type Potassium Channel Modulatory Protein Kcnip1Kv Channel-Interacting Protein 1Kchip1Potassium Channel-Interacting Protein 1Vesicle Apc-Binding Protein |
| Database Links | Reactome: R-HSA-5576894 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmCell ProjectionDendrite |
| Alternative Antibody Names | Anti-A-Type Potassium Channel Modulatory Protein Kcnip1 antibodyAnti-Kv Channel-Interacting Protein 1 antibodyAnti-Kchip1 antibodyAnti-Potassium Channel-Interacting Protein 1 antibodyAnti-Vesicle Apc-Binding Protein antibodyAnti-KCNIP1 antibodyAnti-KCHIP1 antibodyAnti-VABP antibody |
Information sourced from Uniprot.org