| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KCNH6 |
| Gene ID: |
81033 |
| Uniprot ID: |
KCNH6_HUMAN |
| Immunogen Region: |
70-220 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 70-220 of human KCNH6 (NP_110406.1). |
| Immunogen Sequence: |
TGPNTPSSAVSRLAQALLGA EECKVDILYYRKDASSFRCL VDVVPVKNEDGAVIMFILNF EDLAQLLAKCSSRSLSQRLL SQSFLGSEGSHGRPGGPGPG TGRGKYRTISQIPQFTLNFV EFNLEKHRSSSTTEIEIIAP HKVVERTQNVT |
| Tissue Specificity | Expressed in prolactin-secreting adenomas. |
| Function | Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Characterized by unusual gating kinetics by producing relatively small outward currents during membrane depolarization and large inward currents during subsequent repolarization which reflect a rapid inactivation during depolarization and quick recovery from inactivation but slow deactivation (closing) during repolarization. Activates even more slowly than KCNH2. |
| Protein Name | Voltage-Gated Inwardly Rectifying Potassium Channel Kcnh6Ether-A-Go-Go-Related Gene Potassium Channel 2Erg-2Eag-Related Protein 2Ether-A-Go-Go-Related Protein 2Herg-2Herg2Potassium Voltage-Gated Channel Subfamily H Member 6Voltage-Gated Potassium Channel Subunit Kv11.2 |
| Database Links | Reactome: R-HSA-1296072 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Voltage-Gated Inwardly Rectifying Potassium Channel Kcnh6 antibodyAnti-Ether-A-Go-Go-Related Gene Potassium Channel 2 antibodyAnti-Erg-2 antibodyAnti-Eag-Related Protein 2 antibodyAnti-Ether-A-Go-Go-Related Protein 2 antibodyAnti-Herg-2 antibodyAnti-Herg2 antibodyAnti-Potassium Voltage-Gated Channel Subfamily H Member 6 antibodyAnti-Voltage-Gated Potassium Channel Subunit Kv11.2 antibodyAnti-KCNH6 antibodyAnti-ERG2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
