Western blot analysis of various lysates using KCNH6 Rabbit polyclonal antibody (STJ117717) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 60s.

Anti-KCNH6 antibody (70-220) (STJ117717)

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STJ117717
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:200-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KCNH6
Gene ID: 81033
Uniprot ID: KCNH6_HUMAN
Immunogen Region: 70-220
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 70-220 of human KCNH6 (NP_110406.1).
Immunogen Sequence: TGPNTPSSAVSRLAQALLGA EECKVDILYYRKDASSFRCL VDVVPVKNEDGAVIMFILNF EDLAQLLAKCSSRSLSQRLL SQSFLGSEGSHGRPGGPGPG TGRGKYRTISQIPQFTLNFV EFNLEKHRSSSTTEIEIIAP HKVVERTQNVT
Tissue Specificity Expressed in prolactin-secreting adenomas.
Function Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Characterized by unusual gating kinetics by producing relatively small outward currents during membrane depolarization and large inward currents during subsequent repolarization which reflect a rapid inactivation during depolarization and quick recovery from inactivation but slow deactivation (closing) during repolarization. Activates even more slowly than KCNH2.
Protein Name Voltage-Gated Inwardly Rectifying Potassium Channel Kcnh6
Ether-A-Go-Go-Related Gene Potassium Channel 2
Erg-2
Eag-Related Protein 2
Ether-A-Go-Go-Related Protein 2
Herg-2
Herg2
Potassium Voltage-Gated Channel Subfamily H Member 6
Voltage-Gated Potassium Channel Subunit Kv11.2
Database Links Reactome: R-HSA-1296072
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Voltage-Gated Inwardly Rectifying Potassium Channel Kcnh6 antibody
Anti-Ether-A-Go-Go-Related Gene Potassium Channel 2 antibody
Anti-Erg-2 antibody
Anti-Eag-Related Protein 2 antibody
Anti-Ether-A-Go-Go-Related Protein 2 antibody
Anti-Herg-2 antibody
Anti-Herg2 antibody
Anti-Potassium Voltage-Gated Channel Subfamily H Member 6 antibody
Anti-Voltage-Gated Potassium Channel Subunit Kv11.2 antibody
Anti-KCNH6 antibody
Anti-ERG2 antibody

Information sourced from Uniprot.org

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