| Tissue Specificity | Highest expression in testis with moderate levels in colon, placenta, prostate and ovary and low levels in brain, spleen, liver and small intestine. |
| Function | Acts as a transcriptional corepressor of orphan nuclear receptor NR2C2. Inhibits expression of the gluconeogenesis enzyme PCK2 through inhibition of NR2C2 activity. Also involved in transcriptional activation of NAMPT by promoting expression of PPARA and PPARD. Plays a role in lipid metabolism by suppressing lipogenesis, increasing lipolysis and decreasing lipid accumulation in adipose tissue. Plays a role in glucose homeostasis by improving glucose metabolism and insulin sensitivity. |
| Protein Name | Juxtaposed With Another Zinc Finger Protein 1Tak1-Interacting Protein 27Zinc Finger Protein 802 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Juxtaposed With Another Zinc Finger Protein 1 antibodyAnti-Tak1-Interacting Protein 27 antibodyAnti-Zinc Finger Protein 802 antibodyAnti-JAZF1 antibodyAnti-TIP27 antibodyAnti-ZNF802 antibody |
Information sourced from Uniprot.org
