| Tissue Specificity | Ubiquitously expressed in fetal and adult tissues. Localized to the outer segments and connecting cilia of photoreceptor cells. Up-regulated in a number of primary colorectal and gastric tumors. |
| Function | Involved in ciliogenesis. The function in an early step in cilia formation depends on its association with CEP290/NPHP6. Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2 and BBS5 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating CEP290/NPHP6. |
| Protein Name | Iq Calmodulin-Binding Motif-Containing Protein 1Nephrocystin-5P53 And Dna Damage-Regulated Iq Motif ProteinPiq |
| Database Links | Reactome: R-HSA-5620912 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCentrioleLocalization To The Centrosome Depends On The Interaction With Cep290/Nphp6 |
| Alternative Antibody Names | Anti-Iq Calmodulin-Binding Motif-Containing Protein 1 antibodyAnti-Nephrocystin-5 antibodyAnti-P53 And Dna Damage-Regulated Iq Motif Protein antibodyAnti-Piq antibodyAnti-IQCB1 antibodyAnti-KIAA0036 antibodyAnti-NPHP5 antibodyAnti-OK antibodyAnti-SW-cl.85 antibody |
Information sourced from Uniprot.org
