Western blot analysis of extracts of various cell lines, using IL13RA1 antibody (STJ28711) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-IL13RA1 antibody (29-427) (STJ28711)

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STJ28711
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Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IL13RA1
Gene ID: 3597
Uniprot ID: I13R1_HUMAN
Immunogen Region: 29-427
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 29-343 of human IL13RA1 (NP_001551.1).
Immunogen Sequence: TETQPPVTNLSVSVENLCTV IWTWNPPEGASSNCSLWYFS HFGDKQDKKIAPETRRSIEV PLNERICLQVGSQCSTNESE KPSILVEKCISPPEGDPESA VTELQCIWHNLSYMKCSWLP GRNTSPDTNYTLYYWHRSLE KIHQCENIFREGQYFGCSFD LTKVKDSSFEQHSVQIMVKD NAGKIKPSFNIVPLTSRVKP DPPHIKNLSFHNDDLYVQWE NPQNFISRCLFYEVEVNNS
Tissue Specificity Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary.lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.
Function Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.
Protein Name Interleukin-13 Receptor Subunit Alpha-1
Il-13 Receptor Subunit Alpha-1
Il-13r Subunit Alpha-1
Il-13r-Alpha-1
Il-13ra1
Cancer/Testis Antigen 19
Ct19
Cd Antigen Cd213a1
Database Links Reactome: R-HSA-6785807
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Interleukin-13 Receptor Subunit Alpha-1 antibody
Anti-Il-13 Receptor Subunit Alpha-1 antibody
Anti-Il-13r Subunit Alpha-1 antibody
Anti-Il-13r-Alpha-1 antibody
Anti-Il-13ra1 antibody
Anti-Cancer/Testis Antigen 19 antibody
Anti-Ct19 antibody
Anti-Cd Antigen Cd213a1 antibody
Anti-IL13RA1 antibody
Anti-IL13R antibody
Anti-IL13RA antibody

Information sourced from Uniprot.org

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