| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | IFI44L |
| Gene ID: | 10964 |
| Uniprot ID: | IF44L_HUMAN |
| Immunogen Region: | 1-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human IFI44L (NP_006811.2). |
| Immunogen Sequence: | MEVTTRLTWNDENHLRKLLG NVSLSLLYKSSVHGGSIEDM VERCSRQGCTITMAYIDYNM IVAFMLGNYINLHESSTEPN DSLWFSLQKKNDTTEIETLL LNTAPKIIDEQLVCRLSKTD IFIICRDNKIYLDKMITRNL KLRFYGHRQYLECEVFRVEG IKDNLDDIKRIIKAREHRNR LLADIRDYRPYADLVSEIRI |
| Function | Type I interferon-stimulated gene (ISG) that plays a critical role in antiviral and antibacterial activity. During bacterial infection, promotes macrophage differentiation and facilitates inflammatory cytokine secretion. Plays a role in the control of respiratory syncytial virus/RSV infection, reducing the ability of the virus to replicate. Exhibits a low antiviral activity against hepatitis C virus. Acts also as a feedback regulator of IFN responses by negatively regulating IKBKB and IKBKE kinase activities through interaction with FKBP5. |
| Protein Name | Interferon-Induced Protein 44-Like |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Interferon-Induced Protein 44-Like antibodyAnti-IFI44L antibodyAnti-C1orf29 antibodyAnti-GS3686 antibody |
Information sourced from Uniprot.org