| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ICE2 |
| Gene ID: | 79664 |
| Uniprot ID: | ICE2_HUMAN |
| Immunogen Region: | 660-800 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 660-800 of human ICE2 (NP_078887.2). |
| Immunogen Sequence: | SRKVPELPLMNLENSKQPSV SEQLSGPSDSSSWPKSGWPS AFQKPKGRLPYELQDYVEDT SEYLAPQEGNFVYKLFSLQD LLLLVRCSVQRIETRPRSKK RKKIRRQFPVYVLPKVEYQA CYGVEALTESELCRLWTESL L |
| Tissue Specificity | Expressed at low levels in lung and testis. |
| Function | Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. |
| Protein Name | Little Elongation Complex Subunit 2Interactor Of Little Elongator Complex Ell Subunit 2Nmda Receptor-Regulated Protein 2 |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | NucleusColocalizes With Coil In Subnuclear Cajal And Histone Locus BodiesTranslocates In The Lec Complex To Cajal And Histone Locus Bodies At Snrna Genes In A Ice1-Dependent MannerAssociates To Transcriptionally Active Chromatin At Snrna Genes |
| Alternative Antibody Names | Anti-Little Elongation Complex Subunit 2 antibodyAnti-Interactor Of Little Elongator Complex Ell Subunit 2 antibodyAnti-Nmda Receptor-Regulated Protein 2 antibodyAnti-ICE2 antibodyAnti-BRCC1 antibodyAnti-NARG2 antibodyAnti-UNQ3101 antibodyAnti-PRO10100 antibody |
Information sourced from Uniprot.org