| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-ICAM4 (169-182) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 28kDa band observed in Human Umbillical Cord and in Erythrocytes lysates (calculated MW of 29.3kDa according to NP_001535.1). Recommended concentration: 1-3µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | ICAM4 |
| Gene ID: | 3386 |
| Uniprot ID: | ICAM4_HUMAN |
| Immunogen Region: | 169-182 |
| Accession Number: | NP_001535.1; NP_071772.1 |
| Specificity: | This antibody is expected to recognize isoform 1 (NP_001535.1) and isoform 2 (NP_071772.1) only. |
| Immunogen Sequence: | RHGSRVIYSESLER |
| Post Translational Modifications | N- and O-glycosylated. |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins. |
| Protein Name | Intercellular Adhesion Molecule 4Icam-4Landsteiner-Wiener Blood Group GlycoproteinLw Blood Group ProteinCd Antigen Cd242 |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-216083 |
| Cellular Localisation | Isoform Long: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform Short: SecretedCell Membrane |
| Alternative Antibody Names | Anti-Intercellular Adhesion Molecule 4 antibodyAnti-Icam-4 antibodyAnti-Landsteiner-Wiener Blood Group Glycoprotein antibodyAnti-Lw Blood Group Protein antibodyAnti-Cd Antigen Cd242 antibodyAnti-ICAM4 antibodyAnti-LW antibody |
Information sourced from Uniprot.org