| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HS6ST1 |
| Gene ID: | 9394 |
| Uniprot ID: | H6ST1_HUMAN |
| Immunogen Region: | 302-411 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 302-411 of human HS6ST1 (NP_004798.3). |
| Immunogen Sequence: | YLFERTFNLKFIRPFMQYNS TRAGGVEVDEDTIRRIEELN DLDMQLYDYAKDLFQQRYQY KRQLERREQRLRSREERLLH RAKEALPREDADEPGRVPTE DYMSHIIEKW |
| Tissue Specificity | Expressed in fetal brain. |
| Post Translational Modifications | N-glycosylated. |
| Function | 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid. |
| Protein Name | Heparan-Sulfate 6-O-Sulfotransferase 1Hs6st-1 |
| Database Links | Reactome: R-HSA-2022928 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Heparan-Sulfate 6-O-Sulfotransferase 1 antibodyAnti-Hs6st-1 antibodyAnti-HS6ST1 antibodyAnti-HS6ST antibody |
Information sourced from Uniprot.org