Tissue Specificity | High expression in liver and pancreas. Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients. |
Function | Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2. Hydrolyzes adenosine 5'-O-p-nitrophenylphosphoramidate (AMP-pNA). Hydrolyzes fluorogenic purine nucleoside tryptamine phosphoramidates in vitro. May be involved in steroid biosynthesis. May play a role in apoptosis. |
Protein Name | Adenosine 5'-Monophosphoramidase Hint2Hint-3Hit-17kdaHistidine Triad Nucleotide-Binding Protein 2 - MitochondrialHint-2Pkci-1-Related Hit Protein |
Database Links | Reactome: R-HSA-9013405 |
Cellular Localisation | Mitochondrion |
Alternative Antibody Names | Anti-Adenosine 5'-Monophosphoramidase Hint2 antibodyAnti-Hint-3 antibodyAnti-Hit-17kda antibodyAnti-Histidine Triad Nucleotide-Binding Protein 2 - Mitochondrial antibodyAnti-Hint-2 antibodyAnti-Pkci-1-Related Hit Protein antibodyAnti-HINT2 antibody |
Information sourced from Uniprot.org