Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-HHV-8 is suitable for use in Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | 13B10 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
Dilution Range: | IHC 1:50 – 1:200 |
Storage Instruction: | Store at 2-8°C upon receipt. |
Background | Human herpesvirus type 8 (HHV-8) is the likely etiological agent of Kaposi s sarcoma (KS). HHV-8 DNA sequences have been found in Kaposi s sarcoma lesions, primary effusion lymphoma, and multicentric Castleman s disease via polymerase chain reaction and in situ hybridization. Latent nuclear antigen (LNA1, LNA, LANA-1) , also known as ORF73, is a 222-or 234 kD protein that is consistently expressed in HHV8 infected cells. Anti-HHV-8 labels the latent nuclear antigen protein via immunohistochemistry |
Information sourced from Uniprot.org