| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GYS2 (594-703) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GYS2 |
| Gene ID: |
2998 |
| Uniprot ID: |
GYS2_HUMAN |
| Immunogen Region: |
594-703 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 594-703 of human GYS2 (NP_068776.2). |
| Immunogen Sequence: |
DLLDWRYLGRYYQHARHLTL SRAFPDKFHVELTSPPTTEG FKYPRPSSVPPSPSGSQASS PQSSDVEDEVEDERYDEEEE AERDRLNIKSPFSLSHVPHG KKKLHGEYKN |
| Post Translational Modifications | Primed phosphorylation at Ser-657 (site 5) by CSNK2A1 and CSNK2A2 is required for inhibitory phosphorylation at Ser-641 (site 3a), Ser-645 (site 3b), Ser-649 (site 3c) and Ser-653 (site 4) by GSK3A an GSK3B. Dephosphorylation at Ser-641 and Ser-645 by PP1 activates the enzyme. Phosphorylation at Ser-8 is not required for interaction with GYG1. Interaction with GYG1 does not regulate the phosphorylation at Ser-8 and Ser-641. |
| Function | Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. |
| Protein Name | Glycogen Starch Synthase - Liver |
| Database Links | Reactome: R-HSA-3322077Reactome: R-HSA-3858516Reactome: R-HSA-3878781 |
| Alternative Antibody Names | Anti-Glycogen Starch Synthase - Liver antibodyAnti-GYS2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
