• Western blot analysis of lysates from rat brain, using GRIP1 Rabbit polyclonal antibody (STJ118930) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-GRIP1 antibody (700-950) (STJ118930)

SKU:
STJ118930

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Host: Rabbit
Applications: WB
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GRIP1 (700-950) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GRIP1
Gene ID: 23426
Uniprot ID: GRIP1_HUMAN
Immunogen Region: 700-950
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 700-950 of human GRIP1 (NP_001171545.1).
Immunogen Sequence: KKQTDAQSASSPKKFPISSH LSDLGDVEEDSSPAQKPGKL SDMYPSTVPSVDSAVDSWDG SAIDTSYGTQGTSFQASGYN FNTYDWRSPKQRGSLSPVTK PRSQTYPDVGLSYEDWDRST ASGFAGAADSAETEQEENFW SQALEDLETCGQSGILRELE ATIMSGSTMSLNHEAPTPRS QLGRQASFQERSSSRPHYSQ TTRSNTLPSDVGRKSVTLRK MKQEIKEIMSPTPVELHKV
Function May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons. Through complex formation with NSG1, GRIA2 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting.
Protein Name Glutamate Receptor-Interacting Protein 1
Grip-1
Database Links Reactome: R-HSA-416993
Cellular Localisation Cytoplasmic Vesicle
Perikaryon
Cell Projection
Dendrite
Cytoplasm
Endomembrane System
Peripheral Membrane Protein
Postsynaptic Cell Membrane
Postsynaptic Density
Endoplasmic Reticulum Membrane
Membrane-Associated With Vesicles
Peri-Golgi Complexes And Endoplasmic Reticulum
Enriched In Postsynaptic Plasma Membrane And Postsynaptic Densities
Alternative Antibody Names Anti-Glutamate Receptor-Interacting Protein 1 antibody
Anti-Grip-1 antibody
Anti-GRIP1 antibody

Information sourced from Uniprot.org

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