Function | Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid. Cannot form functional channels on its own and produces channel activity only in heteromeric assembly with GRIK1 and GRIK2 subunits. Can form functional heteromeric receptors with GRIK3. |
Protein Name | Glutamate Receptor Ionotropic - Kainate 5Gluk5Excitatory Amino Acid Receptor 2Eaa2Glutamate Receptor Ka-2Ka2 |
Database Links | Reactome: R-HSA-451308 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Cell MembranePresynaptic Cell MembraneAssociation With Grik2 Is Required For Its Cell Membrane Localization And Channel Activity |
Alternative Antibody Names | Anti-Glutamate Receptor Ionotropic - Kainate 5 antibodyAnti-Gluk5 antibodyAnti-Excitatory Amino Acid Receptor 2 antibodyAnti-Eaa2 antibodyAnti-Glutamate Receptor Ka-2 antibodyAnti-Ka2 antibodyAnti-GRIK5 antibodyAnti-GRIK2 antibody |
Information sourced from Uniprot.org