| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GREM2 (1-60) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GREM2 |
| Gene ID: |
64388 |
| Uniprot ID: |
GREM2_HUMAN |
| Immunogen Region: |
1-60 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human GREM2 (NP_071914.3). |
| Immunogen Sequence: |
MFWKLSLSLFLVAVLVKVAE ARKNRPAGAIPSPYKDGSSN NSERWQHQIKEVLASSQEAL |
| Post Translational Modifications | N-glycosylated. |
| Function | Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells. |
| Protein Name | Gremlin-2Cysteine Knot Superfamily 1 - Bmp Antagonist 2Dan Domain Family Member 3Protein Related To Dan And Cerberus |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Gremlin-2 antibodyAnti-Cysteine Knot Superfamily 1 - Bmp Antagonist 2 antibodyAnti-Dan Domain Family Member 3 antibodyAnti-Protein Related To Dan And Cerberus antibodyAnti-GREM2 antibodyAnti-CKTSF1B2 antibodyAnti-DAND3 antibodyAnti-PRDC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
