| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPRASP1 |
| Gene ID: | 9737 |
| Uniprot ID: | GASP1_HUMAN |
| Immunogen Region: | 200-500 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-500 of human GPRASP1 (NP_055525.3). |
| Immunogen Sequence: | SSLFWSGDEVTAKFHPGNRV KDSNRSMHMANQEANTMSRS QTNQELYIASSSGSEDESVK TPWFWARDKTNTWSGPREDP NSRSRFRSKKEVYVESSSGS EHEDHLESWFGAGKEAKFRS KMRAGKEANNRARHRAKREA CIDFMPGSIDVIKKESCFWP EENANTFSRPMIKKEARARA MTKEEAKTKARARAKQEARS EEEALIGTWFWATDESSMAD EASIESSLQVEDESIIGSW |
| Tissue Specificity | Expressed in the brain, with lower expression in medulla, spinal cord and substantia nigra. |
| Function | Modulates lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. Targets receptors for degradation in lysosomes via its interaction with BECN2. |
| Protein Name | G-Protein Coupled Receptor-Associated Sorting Protein 1Gasp-1 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-G-Protein Coupled Receptor-Associated Sorting Protein 1 antibodyAnti-Gasp-1 antibodyAnti-GPRASP1 antibodyAnti-GASP antibodyAnti-KIAA0443 antibody |
Information sourced from Uniprot.org