| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPHA2 |
| Gene ID: | 170589 |
| Uniprot ID: | GPHA2_HUMAN |
| Immunogen Region: | 24-129 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-129 of human GPHA2 (NP_570125.1). |
| Immunogen Sequence: | QEAVIPGCHLHPFNVTVRSD RQGTCQGSHVAQACVGHCES SAFPSRYSVLVASGYRHNIT SVSQCCTISGLKKVKVQLQC VGSRREELEIFTARACQCDM CRLSRY |
| Tissue Specificity | Found in a variety of tissues. |
| Post Translational Modifications | Glycosylated. |
| Function | Functions as a heterodimeric glycoprotein hormone with GPHB5 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism. |
| Protein Name | Glycoprotein Hormone Alpha-2Putative Secreted Protein Zsig51Thyrostimulin Subunit Alpha |
| Database Links | Reactome: R-HSA-375281Reactome: R-HSA-418555 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Glycoprotein Hormone Alpha-2 antibodyAnti-Putative Secreted Protein Zsig51 antibodyAnti-Thyrostimulin Subunit Alpha antibodyAnti-GPHA2 antibodyAnti-GPA2 antibodyAnti-ZSIG51 antibody |
Information sourced from Uniprot.org