Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-GPHA2 (24-129) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
GPHA2 |
Gene ID: |
170589 |
Uniprot ID: |
GPHA2_HUMAN |
Immunogen Region: |
24-129 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 24-129 of human GPHA2 (NP_570125.1). |
Immunogen Sequence: |
QEAVIPGCHLHPFNVTVRSD RQGTCQGSHVAQACVGHCES SAFPSRYSVLVASGYRHNIT SVSQCCTISGLKKVKVQLQC VGSRREELEIFTARACQCDM CRLSRY |
Tissue Specificity | Found in a variety of tissues. |
Post Translational Modifications | Glycosylated. |
Function | Functions as a heterodimeric glycoprotein hormone with GPHB5 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism. |
Protein Name | Glycoprotein Hormone Alpha-2Putative Secreted Protein Zsig51Thyrostimulin Subunit Alpha |
Database Links | Reactome: R-HSA-375281Reactome: R-HSA-418555 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Glycoprotein Hormone Alpha-2 antibodyAnti-Putative Secreted Protein Zsig51 antibodyAnti-Thyrostimulin Subunit Alpha antibodyAnti-GPHA2 antibodyAnti-GPA2 antibodyAnti-ZSIG51 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance