| Tissue Specificity | Ubiquitously expressed. Expressed at higher level in spleen and placenta. Expressed at lower level in other tissues. In digestive tissues, it is expressed in stomach, duodenum, ileocecum, ileum, jejunum, ascending colon, transverse colon, descending colon, cecum and liver, but not in esophagus and rectum. |
| Function | Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. |
| Protein Name | G-Protein Coupled Bile Acid Receptor 1G-Protein Coupled Receptor Gpcr19Hgpcr19Membrane-Type Receptor For Bile AcidsM-BarHbg37Bg37 |
| Database Links | Reactome: R-HSA-373076Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-G-Protein Coupled Bile Acid Receptor 1 antibodyAnti-G-Protein Coupled Receptor Gpcr19 antibodyAnti-Hgpcr19 antibodyAnti-Membrane-Type Receptor For Bile Acids antibodyAnti-M-Bar antibodyAnti-Hbg37 antibodyAnti-Bg37 antibodyAnti-GPBAR1 antibodyAnti-TGR5 antibody |
Information sourced from Uniprot.org
