| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPAA1 |
| Gene ID: | 8733 |
| Uniprot ID: | GPAA1_HUMAN |
| Immunogen Region: | 90-310 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-310 of human GPAA1 (NP_003792.1). |
| Immunogen Sequence: | AWLERTMRSVGLEVYTQSFS RKLPFPDETHERYMVSGTNV YGILRAPRAASTESLVLTVP CGSDSTNSQAVGLLLALAAH FRGQIYWAKDIVFLVTEHDL LGTEAWLEAYHDVNVTGMQS SPLQGRAGAIQAAVALELSS DVVTSLDVAVEGLNGQLPNL DLLNLFQTFCQKGGLLCTLQ GKLQPEDWTSLDGPLQGLQT LLLMVLRQASGRPHGSHGLF L |
| Tissue Specificity | Ubiquitously expressed in fetal and adult tissues. Expressed at higher levels in fetal tissues than adult tissues. |
| Function | Component of the GPI transamidase complex, necessary for transfer of GPI to proteins. Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate. |
| Protein Name | Glycosylphosphatidylinositol Anchor Attachment 1 ProteinGpi Anchor Attachment Protein 1Gaa1 Protein HomologHgaa1 |
| Database Links | Reactome: R-HSA-162791 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Glycosylphosphatidylinositol Anchor Attachment 1 Protein antibodyAnti-Gpi Anchor Attachment Protein 1 antibodyAnti-Gaa1 Protein Homolog antibodyAnti-Hgaa1 antibodyAnti-GPAA1 antibodyAnti-GAA1 antibody |
Information sourced from Uniprot.org