Anti-GOLPH3 antibody (1-298) (STJ115087)

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STJ115087
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GOLPH3
Gene ID: 64083
Uniprot ID: GOLP3_HUMAN
Immunogen Region: 1-298
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-298 of human GOLPH3 (NP_071413.1).
Immunogen Sequence: MTSLTQRSSGLVQRRTEASR NAADKERAAGGGAGSSEDDA QSRRDEQDDDDKGDSKETRL TLMEEVLLLGLKDREGYTSF WNDCISSGLRGCMLIELALR GRLQLEACGMRRKSLLTRKV ICKSDAPTGDVLLDEALKHV KETQPPETVQNWIELLSGET WNPLKLHYQLRNVRERLAKN LVEKGVLTTEKQNFLLFDMT THPLTNNNIKQRLIKKVQEA VLDKWVNDPHRMDRRLLAL
Tissue Specificity Detected in muscle fibers of patients with mitochondrial diseases.not detected in normal muscle fibers.
Post Translational Modifications Phosphorylated.
Function Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Has also been involved in the control of the localization of Golgi enzymes through interaction with their cytoplasmic part. May play an indirect role in cell migration. Has also been involved in the modulation of mTOR signaling. May also be involved in the regulation of mitochondrial lipids biosynthesis.
Protein Name Golgi Phosphoprotein 3
Coat Protein Gpp34
Mitochondrial Dna Absence Factor
Midas
Cellular Localisation Golgi Apparatus
Golgi Stack Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Trans-Golgi Network Membrane
Mitochondrion Intermembrane Space
Cell Membrane
Endosome
Phosphatidylinositol 4-Phosphate-Binding And Oligomerization Participate In The Recruitment Onto Golgi Membranes
Alternative Antibody Names Anti-Golgi Phosphoprotein 3 antibody
Anti-Coat Protein Gpp34 antibody
Anti-Mitochondrial Dna Absence Factor antibody
Anti-Midas antibody
Anti-GOLPH3 antibody
Anti-GPP34 antibody

Information sourced from Uniprot.org