Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Gene Symbol: |
GNLY |
Gene ID: |
10578 |
Uniprot ID: |
GNLY_HUMAN |
Immunogen Region: |
23-145 aa |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 23-145 of human GNLY (NP_006424.2). |
Immunogen Sequence: |
RLSPEYYDLARAHLRDEEKS CPCLAQEGPQGDLLTKTQEL GRDYRTCLTIVQKLKKMVDK PTQRSVSNAATRVCRTGRSR WRDVCRNFMRRYQSRVTQGL VAGETAQQICEDLRLCIPST GPL |
Tissue Specificity | Expressed in natural killer and T-cells. |
Post Translational Modifications | A 9 kDa form is produced by proteolytic processing of a 15 kDa protein. |
Function | Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis. |
Protein Name | GranulysinLymphokine Lag-2Protein Nkg5T-Cell Activation Protein 519 |
Database Links | Reactome: R-HSA-6803157 |
Cellular Localisation | SecretedLocated In The Cytotoxic Granules Of T-CellsWhich Are Released Upon Antigen Stimulation |
Alternative Antibody Names | Anti-Granulysin antibodyAnti-Lymphokine Lag-2 antibodyAnti-Protein Nkg5 antibodyAnti-T-Cell Activation Protein 519 antibodyAnti-GNLY antibodyAnti-LAG2 antibodyAnti-NKG5 antibodyAnti-TLA519 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance