| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | GNLY |
| Gene ID: | 10578 |
| Uniprot ID: | GNLY_HUMAN |
| Immunogen Region: | 23-145 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-145 of human GNLY (NP_006424.2). |
| Immunogen Sequence: | RLSPEYYDLARAHLRDEEKS CPCLAQEGPQGDLLTKTQEL GRDYRTCLTIVQKLKKMVDK PTQRSVSNAATRVCRTGRSR WRDVCRNFMRRYQSRVTQGL VAGETAQQICEDLRLCIPST GPL |
| Tissue Specificity | Expressed in natural killer and T-cells. |
| Post Translational Modifications | A 9 kDa form is produced by proteolytic processing of a 15 kDa protein. |
| Function | Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis. |
| Protein Name | GranulysinLymphokine Lag-2Protein Nkg5T-Cell Activation Protein 519 |
| Database Links | Reactome: R-HSA-6803157 |
| Cellular Localisation | SecretedLocated In The Cytotoxic Granules Of T-CellsWhich Are Released Upon Antigen Stimulation |
| Alternative Antibody Names | Anti-Granulysin antibodyAnti-Lymphokine Lag-2 antibodyAnti-Protein Nkg5 antibodyAnti-T-Cell Activation Protein 519 antibodyAnti-GNLY antibodyAnti-LAG2 antibodyAnti-NKG5 antibodyAnti-TLA519 antibody |
Information sourced from Uniprot.org