| Host: |
Rabbit |
| Applications: |
DB/ELISA |
| Reactivity: |
Species independent |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4063RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
DB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Specificity: |
Gm |
| Immunogen Sequence: |
Gm conjugated to KLH |
| Background | RNA methylation plays a significant regulatory role in various of physiological activities and it has gradually become a hotspot of epigenetics in the past decade. 2 NA-O-methyladenosine (Am) , 2 NA-O-methylguanosine (Gm) , 2 NA-O-methylcytidine (Cm) , 2 NA-O-methyluridine (Um) , N 6-methyladenosine (m6A) , N 1-methylguanosine (m1G) , 5-methylcytidine (m5C) , and 5-methyluridine (m5U) are representative 2 NA-O-methylation and base-methylation modified epigenetic marks of RNA. 2 NA-O-methyltransferase is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2 NA-O-methyltransferase, using S-adenosyl-L-methionine as a substrate. Through its interaction with other modified nucleosides, 2 NA-O-methylguanosine is thought to stabilize the structure of the tRNA. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
