STJ71310 (0. 5µg/ml) staining of Human Brain (Substantia Nigra) lysate (35µg protein in RIPA buffer). Detected by chemiluminescence.

Anti-GIRK2/KCNJ6 antibody (C-Term) (STJ71310)

SKU:
STJ71310-100
£312.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Goat
Applications: Pep-ELISA/WB/ICC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-GIRK2/KCNJ6 (C-Term) is suitable for use in ELISA, Western Blot and Immunocytochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:32000.
WB: Approx 48kDa band observed in Human Brain (Hippocampus and Substantia Nigra) lysates (calculated MW of 48.5kDa according to NP_002231.1). Recommended concentration: 2-6µg/ml. Primary i
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: KCNJ6
Gene ID: 3763
Uniprot ID: KCNJ6_HUMAN
Immunogen Region: C-Term
Accession Number: NP_002231.1
Immunogen Sequence: SSKLNQHAELET
Function This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Protein Name G Protein-Activated Inward Rectifier Potassium Channel 2
Girk-2
Bir1
Inward Rectifier K(+ Channel Kir3.2
Katp-2
Potassium Channel - Inwardly Rectifying Subfamily J Member 6
Database Links Reactome: R-HSA-1296041
Reactome: R-HSA-997272
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-G Protein-Activated Inward Rectifier Potassium Channel 2 antibody
Anti-Girk-2 antibody
Anti-Bir1 antibody
Anti-Inward Rectifier K(+ Channel Kir3.2 antibody
Anti-Katp-2 antibody
Anti-Potassium Channel - Inwardly Rectifying Subfamily J Member 6 antibody
Anti-KCNJ6 antibody
Anti-GIRK2 antibody
Anti-KATP2 antibody
Anti-KCNJ7 antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ193158 Anti-KCNJ6 antibody (STJ193158) Rabbit Polyclonal Human/Mouse/Rat IHC/IF/WB
STJ501166 Anti-GIRK2 antibody (1-50) (STJ501166) Rabbit Polyclonal Human/Mouse/Rat ELISA/IP/WB
STJ111976 Anti-KCNJ6 antibody (1-80) (STJ111976) Rabbit Polyclonal Human/Mouse WB/ELISA
STJ501167 Anti-GIRK2 antibody (1-50) {Biotin} (STJ501167) Rabbit Polyclonal Human/Mouse/Rat ELISA/IP/WB
STJ501168 Anti-GIRK2 antibody (1-50) {FITC} (STJ501168) Rabbit Polyclonal Human/Mouse/Rat ELISA/IP/WB
STJ112539 Anti-LRP8 antibody (C-Term) (STJ112539) Rabbit Polyclonal Human/Rat WB/IHC-P/IF/ICC/ELISA
STJ116815 Anti-RYBP antibody (C-Term) (STJ116815) Rabbit Polyclonal Mouse/Rat WB/ELISA
STJ117355 Anti-BTBD1 antibody (C-Term) (STJ117355) Rabbit Polyclonal Mouse WB/ELISA
STJ117311 Anti-S1PR4 antibody (C-Term) (STJ117311) Rabbit Polyclonal Human WB/ELISA
!