Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:1000-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | GDF10 |
Gene ID: | 2662 |
Uniprot ID: | GDF10_HUMAN |
Immunogen Region: | 369-478 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 369-478 of human GDF10 (NP_004953.1). |
Immunogen Sequence: | QWDEPRVCSRRYLKVDFADI GWNEWIISPKSFDAYYCAGA CEFPMPKIVRPSNHATIQSI VRAVGIIPGIPEPCCVPDKM NSLGVLFLDENRNVVLKVYP NMSVDTCACR |
Tissue Specificity | Expressed in femur, brain, lung, skeletal muscle, pancreas and testis. |
Function | Growth factor involved in osteogenesis and adipogenesis. Plays an inhibitory role in the process of osteoblast differentiation via SMAD2/3 pathway. Plays an inhibitory role in the process of adipogenesis. |
Protein Name | Growth/Differentiation Factor 10 Gdf-10 Bone Morphogenetic Protein 3b Bmp-3b Bone-Inducing Protein Bip |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Growth/Differentiation Factor 10 antibody Anti-Gdf-10 antibody Anti-Bone Morphogenetic Protein 3b antibody Anti-Bmp-3b antibody Anti-Bone-Inducing Protein antibody Anti-Bip antibody Anti-GDF10 antibody Anti-BMP3B antibody |
Information sourced from Uniprot.org