| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GDF10 |
| Gene ID: | 2662 |
| Uniprot ID: | GDF10_HUMAN |
| Immunogen Region: | 369-478 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 369-478 of human GDF10 (NP_004953.1). |
| Immunogen Sequence: | QWDEPRVCSRRYLKVDFADI GWNEWIISPKSFDAYYCAGA CEFPMPKIVRPSNHATIQSI VRAVGIIPGIPEPCCVPDKM NSLGVLFLDENRNVVLKVYP NMSVDTCACR |
| Tissue Specificity | Expressed in femur, brain, lung, skeletal muscle, pancreas and testis. |
| Function | Growth factor involved in osteogenesis and adipogenesis. Plays an inhibitory role in the process of osteoblast differentiation via SMAD2/3 pathway. Plays an inhibitory role in the process of adipogenesis. |
| Protein Name | Growth/Differentiation Factor 10Gdf-10Bone Morphogenetic Protein 3bBmp-3bBone-Inducing ProteinBip |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Growth/Differentiation Factor 10 antibodyAnti-Gdf-10 antibodyAnti-Bone Morphogenetic Protein 3b antibodyAnti-Bmp-3b antibodyAnti-Bone-Inducing Protein antibodyAnti-Bip antibodyAnti-GDF10 antibodyAnti-BMP3B antibody |
Information sourced from Uniprot.org