| Post Translational Modifications | N-glycosylated. |
| Function | Hydrolyzes the phosphodiester bond of glycerophosphodiesters such as glycerophosphoinositol (GroPIns) and glycerophosphoethanolamine (GroPEth), to yield a glycerol phosphate and an alcohol. Hydrolyzes glycerophospho-N-acylethanolamines to N-acylethanolamines in the brain and participates in bioactive N-acylethanolamine biosynthesis such as anandamide (an endocannabinoid), N-palmitoylethanolamine (an anti-inflammatory), and N-oleoylethanolamine (an anorexic). In addition, has a lysophospholipase D activity by hydrolyzing N-acyl-lysoplasmenylethanolamine (N-acyl-lysoPlsEt) to N-acylethanolamine. However lysophospholipase D activity is lower than glycerophosphodiester phosphodiesterase activity. Has little or no activity towards glycerophosphocholine. |
| Protein Name | Glycerophosphodiester Phosphodiesterase 1Glycerophosphoinositol Glycerophosphodiesterase Gde1Lysophospholipase D Gde1Membrane-Interacting Protein Of Rgs16Rgs16-Interacting Membrane Protein |
| Database Links | Reactome: R-HSA-6814848 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCytoplasmic Vesicle MembranePerinuclear Vesicles And Cell Membrane |
| Alternative Antibody Names | Anti-Glycerophosphodiester Phosphodiesterase 1 antibodyAnti-Glycerophosphoinositol Glycerophosphodiesterase Gde1 antibodyAnti-Lysophospholipase D Gde1 antibodyAnti-Membrane-Interacting Protein Of Rgs16 antibodyAnti-Rgs16-Interacting Membrane Protein antibodyAnti-GDE1 antibodyAnti-MIR16 antibody |
Information sourced from Uniprot.org
