| Function | Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens. H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis. Preferentially fucosylates soluble lactose and to a lesser extent fucosylates glycolipids gangliosides GA1 and GM1a. |
| Protein Name | Galactoside Alpha-(1 -2-Fucosyltransferase 1Alpha(1 -2ft 1Blood Group H Alpha 2-FucosyltransferaseFucosyltransferase 1Gdp-L-Fucose -Beta-D-Galactoside 2-Alpha-L-Fucosyltransferase 1Type 1 Galactoside Alpha-(1 -2-Fucosyltransferase Fut1Type 2 Galactoside Alpha-(1 -2-Fucosyltransferase Fut1 |
| Database Links | Reactome: R-HSA-9033807Reactome: R-HSA-9840309 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinMembrane-Bound Form In Trans Cisternae Of Golgi |
| Alternative Antibody Names | Anti-Galactoside Alpha-(1 -2-Fucosyltransferase 1 antibodyAnti-Alpha(1 -2ft 1 antibodyAnti-Blood Group H Alpha 2-Fucosyltransferase antibodyAnti-Fucosyltransferase 1 antibodyAnti-Gdp-L-Fucose -Beta-D-Galactoside 2-Alpha-L-Fucosyltransferase 1 antibodyAnti-Type 1 Galactoside Alpha-(1 -2-Fucosyltransferase Fut1 antibodyAnti-Type 2 Galactoside Alpha-(1 -2-Fucosyltransferase Fut1 antibodyAnti-FUT1 antibodyAnti-H antibodyAnti-HSC antibody |
Information sourced from Uniprot.org
