| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FNDC5 |
| Gene ID: |
252995 |
| Uniprot ID: |
FNDC5_HUMAN |
| Immunogen Region: |
113-212 |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 113-212 of human FNDC5 (NP_715637.2). |
| Immunogen Sequence: |
QSPASEPVLFKTPREAEKMA SKNKDEVTMKEMGRNQQLRT GEVLIIVVVLFMWAGVIALF CRQYDIIKDNEPNNNKEKTK SASETSTPEHQGGGLLRSKI |
| Tissue Specificity | Widely expressed, with highest levels in heart. Very low expression, if any, in colon, pancreas and spleen. |
| Post Translational Modifications | The extracellular domain is cleaved and released from the cell membrane. N-Glycosylated. |
| Function | Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue. |
| Protein Name | Fibronectin Type Iii Domain-Containing Protein 5Fibronectin Type Iii Repeat-Containing Protein 2 Cleaved Into - Irisin |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinPeroxisome MembraneImported In Peroxisomes Through The Pex5 Receptor PathwayIrisin: SecretedDetected In The Blood Of Individuals Subjected To Endurance Exercise |
| Alternative Antibody Names | Anti-Fibronectin Type Iii Domain-Containing Protein 5 antibodyAnti-Fibronectin Type Iii Repeat-Containing Protein 2 Cleaved Into - Irisin antibodyAnti-FNDC5 antibodyAnti-FRCP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
