Host: |
Mouse |
Applications: |
IHC-P |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-FLI-1 is suitable for use in Immunohistochemistry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
MRQ-1 |
Conjugation: |
Unconjugated |
Isotype: |
IgG2b |
Formulation: |
Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
Dilution Range: |
IHC 1:25 – 1:100 |
Storage Instruction: |
Store at 2-8°C upon receipt. |
Background | Friend leukemia integration 1 transcription factor (FLI-1) is a protein encoded by the proto-ocogene FLI1. The FLI-1 protein is best known for its critical role in the pathogenesis of ES/pPNET. FLI-1 is normally expressed in endothelial cells and in hematopoietic cells, including T-lymphocytes. The immunohistochemical detection of FLI-1 protein has been shown in studies to be valuable in the discrimination of Ewing sarcoma/peripheral primitive neuroectodermal tumor (ES/pPNET) from most of its potential mimics. ES/pPNET is a rare primary tumor of the bone/soft tissue that resembles other undifferentiated tumors. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance