| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FHOD1 |
| Gene ID: | 29109 |
| Uniprot ID: | FHOD1_HUMAN |
| Immunogen Region: | 1010-1120 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1010-1120 of human FHOD1 (NP_037373.2). |
| Immunogen Sequence: | TRGRMITETEKFSGVAGEAP SNPSVPVAVSSGPGRGDADS HASMKSLLTSRPEDTTHNRR SRGMVQSSSPIMPTVGPSTA SPEEPPGSSLPSDTSDEIMD LLVQSVTKSSP |
| Tissue Specificity | Ubiquitous. Highly expressed in spleen. |
| Post Translational Modifications | Phosphorylated by ROCK1. |
| Function | Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing. |
| Protein Name | Fh1/Fh2 Domain-Containing Protein 1Formin Homolog Overexpressed In Spleen 1FhosFormin Homology 2 Domain-Containing Protein 1 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionBlebPredominantly Cytoplasmic |
| Alternative Antibody Names | Anti-Fh1/Fh2 Domain-Containing Protein 1 antibodyAnti-Formin Homolog Overexpressed In Spleen 1 antibodyAnti-Fhos antibodyAnti-Formin Homology 2 Domain-Containing Protein 1 antibodyAnti-FHOD1 antibodyAnti-FHOS antibodyAnti-FHOS1 antibody |
Information sourced from Uniprot.org