| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FHL1 |
| Gene ID: | 2273 |
| Uniprot ID: | FHL1_HUMAN |
| Immunogen Region: | 27-296 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-296 of human FHL1 (NP_001153171.1). |
| Immunogen Sequence: | RDPLQGKKYVQKDGHHCCLK CFDKFCANTCVECRKPIGAD SKEVHYKNRFWHDTCFRCAK CLHPLANETFVAKDNKILCN KCTTREDSPKCKGCFKAIVA GDQNVEYKGTVWHKDCFTCS NCKQVIGTGSFFPKGEDFYC VTCHETKFAKHCVKCNKAIT SGGITYQDQPWHADCFVCVT CSKKLAGQRFTAVEDQYYCV DCYKNFVAKKCAGCKNPITG FGKGSSVVAYEGQSWHDYC |
| Tissue Specificity | Isoform 1 is highly expressed in skeletal muscle and to a lesser extent in heart, placenta, ovary, prostate, testis, small intestine, colon and spleen. Expression is barely detectable in brain, lung, liver, kidney, pancreas, thymus and peripheral blood leukocytes. Isoform 2 is expressed in brain, skeletal muscle and to a lesser extent in heart, colon, prostate and small intestine. Isoform 3 is expressed in testis, heart and skeletal muscle. |
| Function | May have an involvement in muscle development or hypertrophy. |
| Protein Name | Four And A Half Lim Domains Protein 1Fhl-1Skeletal Muscle Lim-Protein 1SlimSlim-1 |
| Cellular Localisation | Isoform 1: CytoplasmIsoform 3: CytoplasmNucleusIsoform 2: NucleusCytoplasmCytosolPredominantly Nuclear In Myoblasts But Is Cytosolic In Differentiated Myotubes |
| Alternative Antibody Names | Anti-Four And A Half Lim Domains Protein 1 antibodyAnti-Fhl-1 antibodyAnti-Skeletal Muscle Lim-Protein 1 antibodyAnti-Slim antibodyAnti-Slim-1 antibodyAnti-FHL1 antibodyAnti-SLIM1 antibody |
Information sourced from Uniprot.org