Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit monoclonal antibody anti-Fetuin A/AHSG (1-100) is suitable for use in Western Blot research applications. |
Clonality: |
Monoclonal |
Clone ID: |
S5MR |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
AHSG |
Gene ID: |
197 |
Uniprot ID: |
FETUA_HUMAN |
Immunogen Region: |
1-100 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Fetuin A/AHSG (P02765). |
Immunogen Sequence: |
MKSLVLLLCLAQLWGCHSAP HGPGLIYRQPNCDDPETEEA ALVAIDYINQNLPWGYKHTL NQIDEVKVWPQQPSGELFEI EIDTLETTCHVLDPTPVARC |
Tissue Specificity | Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. |
Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. O- and N-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. N-glycan at Asn-156: Hex5HexNAc4.N-glycan heterogeneity at Asn-176: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor). |
Function | Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. |
Protein Name | Alpha-2-Hs-GlycoproteinAlpha-2-Z-GlobulinBa-Alpha-2-GlycoproteinFetuin-A Cleaved Into - Alpha-2-Hs-Glycoprotein Chain A - Alpha-2-Hs-Glycoprotein Chain B |
Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-6798695Reactome: R-HSA-8957275 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Alpha-2-Hs-Glycoprotein antibodyAnti-Alpha-2-Z-Globulin antibodyAnti-Ba-Alpha-2-Glycoprotein antibodyAnti-Fetuin-A Cleaved Into - Alpha-2-Hs-Glycoprotein Chain A - Alpha-2-Hs-Glycoprotein Chain B antibodyAnti-AHSG antibodyAnti-FETUA antibodyAnti-PRO2743 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance